Hair Loss

hair loss

Hair loss

Hair has held social and psychological importance throughout the centuries. Hair loss (alopecia) and scalp problems are very common. Out of 10 males, 6 are suffering from hair loss. this of any kind frequently causes major distress for the patient and can lead to anxiety and depression. At Saundarya City, we provide the best hair fall treatment in Nagpur to resolve all your hair falls and scalp problems with the latest equipment & best-in-class facilities.

Facts to know about Hair:

  • The entire scalp contains about 100,000 pigmented terminal hairs.
  • The average density is about 100 to 125 hairs /cm².
  • The average diameter ranges from 50 to 120 mm.
  • Hair grows approximately 1 cm/month or 0.35 mm/day.
  • The scalp sheds about 100 hairs/day.

Hair Growth Cycle

Every hair follicle undergoes an individual recurring cycle with growing and resting phases:
  • Anagen: This is a growing period, persisting for about 2-8 years. About 80-90% of hairs are in this phase.
  • Catagen Phase: This transition phase lasts for about 3 weeks, during which the hair follicle undergoes programmed apoptosis.
  • Telogen Phase: This is a resting phase that lasts around three months. During the telogen phase, the hair does not grow longer.

Causes of Hair Loss

  • Androgenic Alopecia (Pattern hair loss).
  • Telogen effluvium (Non-pattern hair loss-Generalized).
  • Hyper & Hypothyroidism.
  • Hypoparathyroidism: Calcium levels.
  • Hypopituitarism.
  • Diabetes mellitus.
  • Decreased Serum Ferritin levels: Anemia.
  • Low Serum Protein: Amino acids.
  • Deficiency of Vitamins A, C, E, Zinc, Selenium, Copper, etc.
  • Dieting, Stress, Anxiety & Lack of Sleep.

Additional cause

  • Drugs.
  • Weight loss.
  • Acute blood loss.
  • General anesthesia-Reversible (but may become chronic).
  • Post-partum.

Common Scarring Alopecia

  • Discoid Lupus Erythematosus
  • Lichen Planopilaris
  • Severe Fungal, Viral & Bacterial infections.
  • Trauma or Burns

Androgenic Alopecia (Pattern Hair Loss):

Androgenic alopecia is by far the most common form of alopecia in men and women. The development and occurrence of AGA depend on genetic predisposition and the interaction of endocrine factors.

Pathogenesis: How does Pattern Hair Loss occur?

Androgenic Alopecia involves both genetic and hormonal factors. Different gene loci have been linked to the development of AGA. After puberty, androgen triggers a series of events within these genetically programmed hair follicles, predominantly in the front-parietal scalp area that transforms terminal to miniaturized follicles. In AGA, the hair cycle dynamic changes. The time between the shedding of hair and anagen regrowth becomes longer, leading to a reduction of present hair on the scalp.

Factors Causing Hair Loss:

Genetic Factors: The development of AGA shows a strong genetic involvement. The risk of AGA increases significantly with a positive family history. The Expression of Insulin growth factor (IGF)-1, in the dermal papilla, may play an important role in the development of pattern baldness. Gene locus on chromosome 12(12q22-q23) may be responsible for male pattern baldness. A more recent study shows that 17q21.31 may be the locus for early-onset AGA. CYP17 gene on chromosome 10q24.3 was held responsible for female pattern baldness. Ellis shows there is no role of 5µ-reductase isoenzymes in the causation of male pattern baldness. In the balding scalp, higher expression of the androgen receptor gene was found, which is located at band q12 in the X chromosome. The involvement of the X chromosome in the development of AGA stresses the importance of the maternal line in inheritance.

Hormonal Factors: 5µ-reductase plays a key role in AGA. Two 5µ-reductase isoenzymes are found in dermal papilla cells of beard and scalp follicles. In the balding scalp, a predominance of 5µ-reductase isotype 1 can be found.
All enzymes can be located in the sebaceous gland and different parts of the hair follicle of the scalp skin. Therefore the pilosebaceous unit has the potential to mediate androgenic action without relying on elevated systemic levels or production of testosterone or DHT. Increased levels of AROMATASE (Detoxifying by removal of excess androgens) in females explain the difference in male and female patterns of balding and sparing of the frontal hairline. Increased level of 5µ-androstane-3µ,17b-diol glucuronide and 5µ-reductase hyperactivity was found. Testosterone level is normal.

Facts on Male Pattern Baldness:

  • More than 90% of hair loss problems in men are AGA.
  • Out of 10 males, 6 are suffering from MPB.
  • AGA usually starts at an early age and progresses slowly.
  • Thinning of hair can occur as early as the age of 12 or any time later in life.
  • Most cases start between the age of 15 and 25.
  • The Clinical course is gradual.
  • Many men reach their maximum pattern by their 40s.
  • Usually, there is a strong family history but in about 12% of cases, family history is negative.

Saundarya City has the best doctor for hair falls in Nagpur to help you regain your confidence. Schedule your appointment today and start your journey to healthy hair!

Female Pattern Hair Loss:

Female Pattern Hair falls, also known as Androgenetic Alopecia, is most commonly found in females. Most females with androgenetic alopecia have a history of gradual scalp thinning over a period. Get the best hair fall treatment in Nagpur at Saundarya City.
There is a history of telogen effluvium (Excessive hair loss) which may predate a clinically obvious reduction in hair density showing a widening of central parting with a diffuse reduction in hair density mainly affecting the frontal scalp and crown. The frontal hairline is typically retained.

Ludwig grading is the most commonly used method for FPHL. The Ludwig Classification uses three stages to describe female pattern genetic hair loss:
  • Type I (mild)
  • Type II (moderate)
  • Type III (extensive)

Hair loss can be frustrating, but our best doctor for hair falls treatment in Nagpur at Saundarya City Hospital can help you regain your confidence and your hair.

FAQs about Hair Loss

1.What is alopecia or hair losses?
Normally we have about 1 lac hair follicles on our scalp. These hairs are in the anagen phase (Terminal hairs) which remain for about 8-10 years and fall away giving way for new hair from hair but(root). On average, we lose about 30-50 strands of hair each day. If hair loss is above this standard rate, It is considered hair loss and the best course of action is to seek help from a doctor. Get the best hair loss treatment in Nagpur from Saundarya City.

2.What are the types of hair losses?

There are a few types of hair losses:

  • Diffuse Unpatterned Alopecia (DUPA)
  • Patterned Hair Loss – Male Pattern Baldness(MPB) and Female Pattern Baldness.
  • Scarring(Cicatricial) or Non Scarring(Noncicatricial).

Laboratory Test:
A laboratory workup is usually not required in men and women with Androgenic Alopecia unless there is concomitant diffuse hair losses.
A genetic test can be done (HairDX)
(Images).

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