Gynaecomastia: Gynaecomastia is commonly described as benign ( Noncancer) proliferation of male breast tissue or persistant enlargement of male breast tissue.
32 to 36% of males suffer from gynaecomastia, and as high as 65% in adolescent boys. Bilateral disease is reported to occur in 25-75% of cases
Oestrogen,androgens ad their receptors are thought to play a major role in the development of the condition
An imbalance in the concentrations of the hormone’s, with a relative increase in ostrogen, is thought to bring about breast tissue proliferation.
1) Neonatal-no treatment required(Maternal Oestrogens through placenta). 2) Puberertal: transient development of breast tissue is common in adolescent boy.
A relative increase in plasma estradiol compared to testosterone is thought to cause pubertal gynecomastia.
Due to various metabolic and endocrine disorders. Aquired and congenital hypogonadal states leading to an increased overall estrogen state.
Drugs are major etiological factor. It occurs due to direct increase in ostrogen and decreased testosterone
Medical: Tab Tamoxifen(anti-oestrogen), TabClomiphen( act on hypothalamic pituitary axis to increase LH & FSH) and Tab Danazole( acts on by suppressing pituitary –ovarian axis by inhibiting the out put of both LH & FSH) can be used for spontaneous regression.
The aim of surgical treatmentare volume reduction with or without retailoring of redundant skin.